A bit of science on Friday

Australia is moving

Sadly, it’s towards civilisation (North) rather than away from us all. 7cm a year, to be exact, because of tectonic plate movement. Australia is on the Indian-Australian Plate (can you guess which other country is also on there?) and that plate is moving North, where it collides with the Pacific Plate and the Sunda Plate.

Now, 7cm might not seem like a lot (because it’s not a lot), but there’s been no update of GPS systems and the like since 1994, and now Australia is 1.5m further north than it was back then.

Now, 1.5m might not seem like a lot (because it’s not a lot) (although it’s clearly more than 7cm), but if you are navigating by super-accurate GPS, and the data you’re getting is fundamentally incorrect, then that might have rather serious consequences, as Dan Jaksa from Geoscience Australia told ABC News.

In the not-too-distant future, we are going to have possibly driverless cars or at least autonomous vehicles where, 1.5 metres, well, you’re in the middle of the road or you’re in another lane.

Indeed, so what are they going to do about it?

On 1 January 2017, Australia’s local co-ordinates will be shifted further north – by 1.8m. The over-correction means Australia’s local co-ordinates and the Earth’s global co-ordinates will align in 2020.At that point a new system, which can take changes over time into account, will be implemented.

Can’t we just rather give it a big push back the other way?

Brain Disease

I learned about a disease called kuru when I was at university, but suddenly, it became much more relevant when people worked out that Bovine Spongiform Encephalopathy (BSE, Mad Cow Disease – and its human equivalent CJD – Creutzfeldt-Jakob Disease) had the same causal “agent”.
I use those quotes, because these diseases aren’t caused by bacteria or viruses, but rather prions – tiny strands of protein that gradually destroy the brain. It’s a slow, drawn out, lingering death. And we have no way of stopping it. Any antibacterial or antiviral drug relies on attacking some part of the life cycle of the bug to kill it. Protein strands don’t have life cycles. They’re just protein strands. Prion diseases are (currently) incurable.

What’s interesting about kuru is that it existed solely in remote tribes in Papua New Guinea – specifically the Fore people – who engaged in cannibalism. In many villages:

…when a person died, they would be cooked and consumed. It was an act of love and grief.

“If the body was buried it was eaten by worms; if it was placed on a platform it was eaten by maggots; the Fore believed it was much better that the body was eaten by people who loved the deceased than by worms and insects.”

What’s even more interesting is that these prions attack the nervous system. And the vast majority of the victims were women and children, because traditionally, they were the ones who ate the brains. The elders and men in the tribe were spared the offal, and thus, mostly spared from kuru as well.

There’s more reading on that link above, but the last known kuru victim died in 2009. Sadly, because of the long incubation period of prion diseases (I’m still on 40-year high risk list because I processed patient specimens from suspected CJD cases when I worked in the labs in the UK) we can’t be certain that it’s completely gone, but there have been no cases in the intervening 7 years.

Which probably explains why Australia now thinks it’s safe to drift closer to Papua New Guinea.

Germs, Disease, Infection!

Three health related things for you to know about:

Firstly: Dead reindeer!
You know that awkward feeling when you thought that chronic wasting disease (CWD) was restricted to deer, elk (Cervus canadensis) and moose (Alces alces) in North America and South Korea, but then researchers announce that the disease has been discovered in a free-ranging reindeer (Rangifer tarandus tarandus) in Norway.
Yeah. Exactly. Bad news for free-ranging reindeer in Norway. Glad I’m not going there any time soon.

It is a mystery how this disease arrived on a mountaintop in Norway. Researchers think it unlikely that it was it imported. They suspect that it might have arisen spontaneously, or jumped the species barrier from a prion disease in sheep called scrapie, although such a jump has never been seen before.

Now that it’s there though, history has shown us that it will be hugely difficult to eradicate.
Not great.

Secondly: A comeback!
Scarlet fever struck fear in the hearts of Victorian-era Americans and Europeans. In the late 19th century, it was a leading cause of death in children—killing as many as a third of those who caught the infection.
Not great.
Then suddenly, <sparkly lights>antibiotics!</sparkly lights> and we humans were saved as the Streptococcus spp. succumbed to Alexander Fleming’s penicillin. But now…

…the disease is making a comeback. In 2011, Hong Kong experienced an outbreak that quadrupled in the number of scarlet-fever cases. And, since 2014, England and Wales has been hit by a big outbreak, too. This season, the number of scarlet-fever cases reached a 50-year high.

And no-one knows why. There is no vaccine for Scarlet Fever, so it’s not foolishly impressionable parents making poor decisions based on dodgy “science”. It’s as much a conundrum as CWD in free-ranging reindeer in Norway.
(That’s my new goto metaphor for mysteries now.)

Thirdly: Talking of crimson!
Science, as an entity, was 0-2 down in this post so far, but there’s hope of a late comeback as we snatch a point against the run of play in the treatment of red scrotum syndrome. I’m no expert on this particular condition, but – if pushed – I think I could come up with a guess at both the area affected and the signs and symptoms on said area.
Not great.

We report two cases of red scrotum syndrome responding to oral pregabalin, an anticonvulsant medication commonly used for neuropathic pain. These two cases suggest pregabalin as an effective means for treating red scrotum syndrome and endorse a neuropathic etiology.

Serendipity with the assist on that one, it seems. But either way, I’m sure that anyone suffering with red scrotum syndrome will be relieved to learn that a potential cure has been discovered – by whatever means.