H5N1 – coming soon

With a world suffering with pandemic fatigue, knobhead anti-vaxxers rife everywhere you look, and a general deep distrust of Government-instituted Nonpharmaceutical Interventions (NPIs), an outbreak of something really serious right now couldn’t come at a worse time.

Jimmy Carr: “Do you think we overreacted to Covid-19?”
Audience: “Yes!”
JC: “Yeah, a lot of the survivors think so.”

Jimmy Carr – His Dark Material (2021)

And yet, the warning signs are very much there that Highly Pathogenic Avian Flu (HPAI) (H5N1) has had its fun with the birds and is moving onto mammals. In the US, there have been almost 200 “spillover” infections of mammals with the virus:

On March 29, the USDA first published its data on cases of HPAI infections in mammals from 2022 to late March 2023. The H5N1 virus subtype was detected in numerous species: bobcat, black and brown bears, bottlenose dolphin, harbor and grey seals, mountain lion, red fox, raccoon, striped skunk, and more.

While on the Pacific Coast of South America it’s looking even more serious:

Indeed:

Senapesca made a balance on Monday on the progress of avian influenza in Chile, detailing that a total of 11,471 specimens have died as a result of this influenza.
The authorities confirmed the deaths of 9,853 sea lions, 1,555 Humboldt penguins, 27 chungungos, 21 spiny porpoises, 14 Chilean dolphins and one huillín.

Senapesca is the Ministry of Agriculture and Fisheries in Chile.
Chungungos and huillíns are two different sorts of otter. You live*, you learn.

And sure, the penguins are very much avian, but the rest of them… well… it’s not good news.

It’s important to understand that at the moment, there have been very few human cases of H5N1, and no reports of human to human transmission. So no need to panic. But there are a couple of provisos: firstly, that this is a very nasty virus with a very high mortality rate in the cases we have seen (far, far (far!) higher than SARS-CoV-2), and secondly, we’re potentially only ever one mutation away from that human to human transmission becoming a thing, and the more mammalian infections that we see, the more likely that is to happen.

On the plus side, we have a very good handle on this Influenza virus already. It’s been around for a while and we’ve got a lot of information on its genomics and how it works. That should mean that any vaccine production should be able to be rapidly achieved, and that the product should be very effective.

But then there are all the politics and logistics to slow things down.

It then remains to be seen – in the event of it all going pear-shaped – how many people will actually go and get vaccinated, given the problems detailed in the first paragraph above. But in this case, I can’t see choosing not to as being any more than an accelerated form of natural selection.

Anyway, definitely one to watch out for.
Enjoy your day.

* not if you’re an otter, obviously

Day 241 – Libertador O’Higgins

It sounds like a made up name, doesn’t it?
Something you might find in an off-the-wall comedy skit show.

But no.

Crazy name, crazy guy, crazier legacy!

(Not to be confused with Bernard O’Higgins (?–1564) who was an Irish Roman Catholic bishop. He served as the Bishop of Elphin from 1542 to 1564.) (Obviously.)

I discovered Libertador O’Higgins in Chile thanks to there being an earthquake near there last night:

It turns out that Libertador O’Higgins is a region of Chile, just south of Santiago and named for… well… Libertador Bernardo O’Higgins.

And who was he?
Well:

Bernardo O’Higgins Riquelme (1778–1842) was a Chilean independence leader who freed Chile from Spanish rule in the Chilean War of Independence. He was a wealthy landowner of Spanish and Irish ancestry. Although he was the second Supreme Director of Chile (1817–1823), he is considered one of Chile’s founding fathers, as he was the first holder of this title to head a fully independent Chilean state.

He was Captain General of the Chilean Army, Brigadier of the United Provinces of the Río de la Plata, General Officer of Gran Colombia and Grand Marshal of Peru.

I think that we could have guessed the Irish ancestry bit.

… the illegitimate son of Ambrosio O’Higgins, 1st Marquis of Osorno, a Spanish officer born in County Sligo, Ireland, who became governor of Chile and later viceroy of Peru. His mother was Isabel Riquelme, a prominent local; the daughter of Don Simón Riquelme y Goycolea, a member of the Chillán Cabildo, or town council.

You can read more about his role in the Chilean Independence movement and his time as Supreme Director of Chile – and his part in Peruvian Independence – on that link above.

But this was the bit that got me: he has a really, really impressive array of stuff commemorating him, including (but not limited to):

– an administrative region in Chile (which had an earthquake near it last night)
– a major road in Santiago and a National Park
– a Blue Plaque and a bust in Richmond in London
– plaques, busts and statues in Sydney, Guatemala City, Costa Rica, Buenos Aires, Bogota and Cadiz
– Chile’s highest award for a foreign citizen
– an unorchestrated opera
– 3 ships, a submarine and an Antarctic research base
– a set of stamps in Chile and one in Ireland
– an actual football team

Yes: An. Actual. Football. Team.

 

Amazing.